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Many major discoveries did not begin with a specific plan or immediate success. People set out looking for one thing, took a wrong turn, noticed a strange detail, or realized that a failed attempt had revealed something greater. This is true in geography, where explorers often altered maps by misjudging distances or taking the wrong route. It’s just as true in science, where some of the most important advances have stemmed from mistakes, contamination, or simple surprises. Here are 10 accidental discoveries that redrew the map, and 10 others that revolutionized science.

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